The first thing you need to do is decide how you intend to use the car. Cars guys often waste considerable time and dollars going down one path, only to reverse direction. Will it be a boulevard cruiser or on long highway drives to farther destinations? Show or go? Modified or restored? Local show trophy collector or points judged? Drive it for a season or two then flip it, or get buried in the car?
You can buy as hell of a lot of gas for the price of converting to FI. When you go to sell the car, the non-correct FI unit may even detract from the car's value.
If your car has factory 8-lug wheels, I recommend you keep them on the car. IMO there is no better looking wheel out there, and they are highly prized by Big Pontiac buyers. Roush sold an 8-lug disc brake conversion for awhile, but I'm not certain that they are still available. They required the 15" rims. Check with Larry at 815.735.4002 or
lgto67@yahoo.com (tell him the 2+2 Registry referred you).
There is a company in Texas that makes 15-inch rims to fit the 8-lugs. Coker has the best selection of vintage-look tires, including a new line of radials that have that '50's or '60's appearance. Unfortunately the sizes available may not fit our cars - hopefully the options will improve. If you are not concerned about originality, go with radials. I'm forced to use reproduction bias-plieson my '65 because I frequently drag race with a FAST-class (factory-appearing/stock tire) group, and have the car points-judged at POCI and AACA. My friend has a '65 2+2 coupe which runs on radials, and the smooth ride on his car is far superior to mine.
Best of luck with your choices! Making the car your own is 1/2 the fun - driving it when done (if they ever are done) is the other 1/2.